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Advanced polyostotic fibrous dysplasia

1 Department of Biochemistry, Abdul Malek Ukil Medical College, Noakhali, Bangladesh
2 Department of Emergency and Casualty, Cumilla General Hospital, Cumilla, Bangladesh
3 Department of Endocrinology, Mymensingh Medical College Hospital, Mymensingh, Bangladesh
4 Department of Medicine, Sir Salimmullah Medical College and Mitford Hospital, Dhaka, Bangladesh
5 Department of Rheumatology, Mymensingh Medical College Hospital, Mymensingh, Bangladesh

Correspondence Address:
A B M Kamrul-Hasan,
Department of Endocrinology, Mymensingh Medical College, Mymensingh 2206
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/bjem.bjem_1_22

Polyostotic fibrous dysplasia is a disorder that features the replacement of multiple areas of bone with fibrous tissue, which may cause fractures and deformity. It begins in childhood and progresses onward, affecting both sexes equally. A 23-year-old male presented with recurrent fractures of all long bones and multiple vertebrae with low trauma. X-ray showed extensive multilocular cystic lesions with ground-glass diffuse refractions throughout all long bones, multiple fracture lines and dislocation of joints, scoliosis, and compression of multiple vertebrae. Severe cortical thinning is also seen in all bones. He was managed with bisphosphonate, and significant improvement was observed.

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