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Year : 2023  |  Volume : 2  |  Issue : 1  |  Page : 55-57

Coexistent papillary thyroid carcinoma in a patient with graves' disease

Department of Endocrinology, Mymensingh Medical College, Mymensingh, Bangladesh

Correspondence Address:
A B. M. Kamrul-Hasan
Department of Endocrinology, Mymensingh Medical College, Mymensingh 2206
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/bjem.bjem_16_22

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A 21-year-old male presented with the features of thyrotoxicosis, and his thyroid function tests revealed primary hyperthyroidism. He also had mild bilateral exophthalmos with lid lag, lid retraction, and a clinical activity score of 1, suggestive of mild Graves' ophthalmopathy. Neck ultrasonography revealed mild diffuse goiter with bilateral fairly large nodules predominantly at the right lobe and bilateral multiple cervical lymphadenopathies. Tc-99m pertechnetate scan demonstrated diffuse goiter with homogeneously increased radiotracer concentration. He had an elevated titer of thyroid-stimulating hormone receptor autoantibody level. Fine-needle aspiration cytology from the largest nodule of the right lobe reported a Bethesda Category-VI lesion compatible with papillary thyroid carcinoma. Graves' disease and papillary thyroid cancer carcinoma might be present concomitantly in the same patient. Although links between these entities have long been investigated, a clear correlation is not established yet.

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